The VAF has provided many thousands of dollars in grants supporting research to advance ocular health in animals. Much of this funding has resulted in the publication of research in peer-reviewed scientific journals, indicative of the high quality of grants funded by the VAF. These journal articles are accessible online, providing worldwide access to valuable animal vision research.
2023
The TGM2 inhibitor cysteamine hydrochloride does not impact corneal epithelial and stromal wound healing in vitro and in vivo. Minella AL, Casanova MI, Chokshi TJ, Kang J, Cosert K, Gragg MM, Bowman MA, Mccorkell ME, Daley NL, Leonard BC, Murphy CJ. https://www.sciencedirect.com/science/article/pii/S0014483522004195
Chromatic Pupillometry as a Putative Screening Tool for Heritable Retinal Disease in Rhesus Macaques. Salpeter EM, Moshiri A, Ferneding M, Motta MJ, Park S, Skouritakis C, Thomasy SM. https://tvst.arvojournals.org/article.aspx?articleid=2785721&resultClick=1
Ophthalmic viscoelastics commonly used in cataract surgery: A microbiota investigation. Dowler KK, Vientós‐Plotts A, Giuliano EA, McAdams ZL, Dorfmeyer RA, Reinero CR, Ericsson AC. https://onlinelibrary.wiley.com/doi/10.1111/vop.13068
Topical ropivacaine hydrochloride 0.5% and lidocaine hydrochloride 2% significantly reduce corneal sensitivity without short‐term negative side effects in horses. Minaldi MP, Fidler LE, Betbeze CM, Wills R, Fontenot RL, Telle MR.https://onlinelibrary.wiley.com/doi/10.1111/vop.13137
2022
Evaluation of a novel combination of TRAM-34 and ascorbic acid for the treatment of corneal fibrosis in vivo. Fuchs AA, Balne PK, Giuliano EA, Sinha NR, Mohan RR. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0262046
Molecular and microbiological evidence of bacterial contamination of intraocular lenses commonly used in canine cataract surgery. Dowler KK, Vientós-Plotts A, Giuliano EA, McAdams ZL, Reinero CR, Ericsson AC. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0277753
2020
Tear film concentrations of topically applied 0.5% oxytetracycline ointment in normal canine eyes. Sigmund AB, Ward DA, Cox, SK, Hendrix, DVH. https://onlinelibrary.wiley.com/doi/abs/10.1111/vop.12783
2019
Comparison of two cleaning and sterilization protocols of diamond burr tips used in debridement for canine superficial chronic corneal epithelial defects. Banks KC, Stalla DE, Bunyak FE, White TA, Schultz LG, Giuliano EA. https://www.ncbi.nlm.nih.gov/pubmed/30716201
Determination of trypan blue efficacy in the mitigation of ex vivo canine PCO formation. Brash BM, Gemensky-Metzler AJ, Wilkie DA, Miller EJ, Chandler HL. https://onlinelibrary.wiley.com/doi/abs/10.1111/vop.12669
Diagnostic utility of clinical and laboratory test parameters for differentiating between sudden acquired retinal degeneration syndrome and pituitary-dependent hyperadrenocorticism in dogs. Oh A, Foster ML, Williams JG, Zheng C, Ru H, Lunn KF, Mowat FM. https://doi.org/10.1111/vop.12661
Evaluation of the major histocompatibility complex (MHC) class II as a candidate for sudden acquired retinal degeneration syndrome (SARDS) in Dachshunds. Stromberg SJ, Thomasy SM, Marangakis AD, Kim S, Cooper AE, Brown EA, Maggs DJ, Bannasch DL. https://doi.org/10.1111/vop.12646
2018
Effects of grape seed extract, lutein, and fish oil on responses of canine lens epithelial cells in vitro. Miller EJ, Gemensky-Metzler AJ, Wilkie DA, Wynne RM, Curto EM, Chandler HL. https://doi.org/10.2460/ajvr.79.7.770
Clinical therapeutic efficacy of mycophenolate mofetil in the treatment of SARDS in dogs-a prospective open-label pilot study. Young WM, Oh A, Williams JG, Foster ML, Miller WW, Lunn KF, Mowat FM. https://doi.org/10.1111/vop.12545
2017
Effect of bone marrow-derived mesenchymal stem cells and stem cell supernatant on equine corneal wound healing in vitro. Sherman AB, Gilger BC, Berglund AK, Schnabel LV. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445363/
Effect of topical ophthalmic latanoprost 0.005% solution alone and in combination with diclofenac 0.1% solution in healthy horses: a pilot study. Tofflemire K, Whitley EM, Allbaugh R, Ben-Shlomo G, Griggs A, Strong T, Whitley RD. https://onlinelibrary.wiley.com/doi/full/10.1111/vop.12439
2016
Reduced retinal transduction and enhanced transgene-directed immunogenicity with intravitreal delivery of rAAV following posterior vitrectomy in dogs. RF Boyd, SL Boye, TJ Conlon, KE Erger, DG Sledge, IM Langohr, WW Hauswirth, AM Komáromy, SE Boye, SM Petersen-Jones, JT Bartoe. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891289/
Tear film concentrations of doxycycline following oral administration in ophthalmologically normal dogs. Collins SP, Labelle AL, Dirikolu L, Li Z, Mitchell MA, Hamor RE. https://doi.org/10.2460/javma.249.5.508
Penetration depth of corneal cross-linking with riboflavin and UV-A (CXL) in horses and rabbits. Gallhoefer NS, Spiess BM, Guscetti F, Hilbe M, Hartnack S, Hafezi F, Pot SA. https://onlinelibrary.wiley.com/doi/abs/10.1111/vop.12301
Development of a novel in vivo corneal fibrosis model in the dog. Gronkiewicz KM, Giuliano EA, Kuroki K, Bunyak F, Sharma A, Teixeira LB, Hamm CW, Mohan RR. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684711/
Sudden acquired retinal degeneration syndrome (SARDS) – a review and proposed strategies toward a better understanding of pathogenesis, early diagnosis, and therapy. Komáromy AM, Abrams KL, Heckenlively JR, Lundy SK, Maggs DJ, Leeth CM, MohanKumar PS,Petersen-Jones SM, Serreze DV, van der Woerdt A. https://deepblue.lib.umich.edu/bitstream/handle/2027.42/122446vop12291.pdf?sequence=1&isAllowed=y
Species variation and spatial differences in mucin expression from corneal epithelial cells. Brian C. Leonard, Bernardo Yañez-Soto, Vijay Krishna Raghunathan, Nicholas L. Abbott, Christopher J..Murphy. https://www.sciencedirect.com/science/article/pii/S001448351630241X
Development of a novel ex vivo equine corneal model. Marlo TL, Giuliano EA, Sharma A, Mohan RR. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276793/pdf/nihms-801357.pdf
In vivo ocular imaging of the cornea of the normal female laboratory beagle using confocal microscopy. Strom AR, Cortés DE, Thomasy SM, Kass PH, Mannis MJ, Murphy CJ. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609599/
Histologic and immunohistochemical predictors of clinical behavior for feline diffuse iris melanoma. Wiggans KT, Reilly CM, Kass PH, Maggs DJ. https://onlinelibrary.wiley.com/doi/abs/10.1111/vop.12344
2015
Cyclosporine A prevents ex vivo PCO formation through induction of autophagy-mediated cell death. Chandler HL, Gervais KJ, Lutz EA, Curto EM, Matusow RB, Wilkie DA, Gemensky-Metzler AJ. https://doi.org/10.1016/j.exer.2015.03.020
Oxidative stress increases in retinas of dogs in acute glaucoma but not in chronic glaucoma.Chen T, Gionfriddo JR, Tai PY, Novakowski AN, Alyahya K, Madl JE. https://doi.org/10.1111/vop.12177
Comparison of ultrasound biomicroscopy and standard ocular ultrasonography for detection of canine uveal cysts.Taylor LN, Townsend WM, Heng HG, Stiles J, Moore GE. https://doi.org/10.2460/ajvr.76.6.540
2014
In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites. Groth AD, Contreras MT, Kado-Fong HK, Nguyen KQ, Thomasy SM, Maggs DJ. https://cloudfront.escholarship.org/dist/prd/content/qt124482kj/qt124482kj.pdf
2013
Decorin-PEI nanoconstruct attenuates equine corneal fibroblast differentiation. Donnelly KS, Giuliano EA, Sharma A, Tandon A, Rodier JT, Mohan RR. https://onlinelibrary.wiley.com/doi/abs/10.1111/vop.12060
Diode laser endoscopic cyclophotocoagulation in the normal equine eye. Harrington JT, McMullen RJ Jr, Cullen JM, Campbell NB, Gilger BC. https://doi.org/10.1111/j.1463-5224.2012.01035.x
2012
Canine corneal fibroblast and myofibroblast transduction with AAV5. Bosiack AP, Giuliano EA, Gupta R, Mohan RR. https://doi.org/10.1111/j.1463-5224.2011.00980.x
Induction of posterior capsule opacification by hyaluronic acid in an ex vivo model. Chandler HL, Haeussler DJ Jr, Gemensky-Metzler AJ, Wilkie DA, Lutz EA. https://iovs.arvojournals.org/article.aspx?articleid=2188050
The long-term effects of semiconductor diode laser transscleral cyclophotocoagulation on the normal equine eye and intraocular pressure. Vanessa J. Kuonen Cavens, Anne J Gemensky-Metzler, David A Wilkie, Steven E Weisbrode, Amy M Lehman. https://doi.org/10.1111/j.1463-5224.2012.00996.x
Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. McLean NJ, Ward DA, Hendrix DV, Vaughn RK. https://doi.org/10.2460/javma.240.5.563
Effects of cyclophosphamide myelosuppression in adult dogs with latent canine herpesvirus-1 infection. Mundy P, da Silva EC, Ledbetter EC. https://doi.org/10.1016/j.vetmic.2012.03.019
Immunohistochemical and immunopathologic characterization of superficial stromal immune-mediated keratitis in horses. Pate DO, Clode AB, Olivry T, Cullen JM, Salmon JH, Gilger BC. https://doi.org/10.2460/ajvr.73.7.1067
Pharmacokinetics of penciclovir in healthy cats following oral administration of famciclovir or intravenous infusion of penciclovir. Thomasy SM, Whittem T, Bales JL, Ferrone M, Stanley SD, Maggs DJ. https://doi.org/10.2460/ajvr.73.7.1092
2011
Effect of topical 0.03% flurbiprofen and 0.005% latanoprost, alone and in combination, on normal canine eyes. Pirie CG, Maranda LS, Pizzirani S. https://doi.org/10.1111/j.1463-5224.2010.00832.x
Tear, cornea, and aqueous humor concentrations of ciprofloxacin and moxifloxacin after topical ocular application in ophthalmologically normal horses. Westermeyer HD, Hendrix DV, Ward DA, Cox SK. https://avmajournals.avma.org/doi/abs/10.2460/ajvr.72.3.398
2010
Cellular localization of Visudyne® as a function of time after local injection in an in vivo model of squamous cell carcinoma: an investigation into tumor cell death. Laura D. Barnes, Elizabeth A. Giuliano, Juri Ota. https://doi.org/10.1111/j.1463-5224.2010.00775.x
Neuroinflammation in advanced canine glaucoma. Bing Jiang, Matthew M. Harper, Helga Kecova, Grazyna Adamus, Randy H. Kardon, Sinisa D. Grozdanic, Markus H. Kuehn. http://www.molvis.org/molvis/v16/a225/
Efficacy and safety of mitomycin C as an agent to treat corneal scarring in horses using an in vitro model. Buss DG, Sharma A, Giuliano EA, Mohan RR. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904635/
The effect of topical ocular corticosteroid administration in dogs with experimentally induced latent canine herpesvirus-1 infection. Eric C. Ledbetter, Nathan C. Kice, Rachel B. Matusow, Edward J. Dubovi, Sung G. Kim. https://doi.org/10.1016/j.exer.2010.03.001
Evaluation of 30- and 25-diopter intraocular lens implants in equine eyes after surgical extraction of the lens. McMullen RJ, Davidson MG, Campbell NB, Salmon JH, Gilger BC. https://doi.org/10.2460/ajvr.71.7.809
Effectiveness of injection of local anesthetic into the retrobulbar space for postoperative analgesia following eye enucleation in dogs. Myrna KE, Bentley E, Smith LJ. https://doi.org/10.2460/javma.237.2.174
Canine pre-iridal fibrovascular membranes: morphologic and immunohistochemical investigations. Zarfoss MK, Breaux CB, Whiteley HE, Hamor RE, Flaws JA, Labelle P, Dubielzig RR.. https://doi.org/10.1111/j.1463-5224.2009.00739.x
2009
The effect of photodynamic therapy on squamous cell carcinoma in a murine model: evaluation of time between intralesional injection to laser irradiation.Barnes LD, Giuliano EA, Ota J, Cohn LA, Moore CP. https://doi.org/10.1016/j.tvjl.2007.11.023
Pathogenic phenotype and genotype of Pseudomonas aeruginosa isolates from spontaneous canine ocular infections. Ledbetter EC, Mun JJ, Kowbel D, Fleiszig SM. https://iovs.arvojournals.org/article.aspx?articleid=2185142
Selenium functionalized intraocular lenses inhibit posterior capsule opacification in an ex vivo canine lens capsular bag assay. Pot SA, Chandler HL, Colitz CM, Bentley E, Dubielzig RR, Mosley TS, Reid TW, Murphy CJ. https://doi.org/10.1016/j.exer.2009.06.016
2008
Photodynamic therapy for the treatment of periocular squamous cell carcinoma in horses: a pilot study. Giuliano EA, MacDonald I, McCaw DL, Dougherty TJ, Klauss G, Ota J, Pearce JW, Johnson PJ. https://doi.org/10.1111/j.1463-5224.2008.00643.x
Local photodynamic therapy for equine squamous cell carcinoma: evaluation of a novel treatment method in a murine model. Ota J, Giuliano EA, Cohn LA, Lewis MR, Moore CP. https://doi.org/10.1016/j.tvjl.2007.06.025
2007
Prevalence of feline herpesvirus 1, Chlamydophila felis, and Mycoplasma spp DNA in conjunctival cells collected from cats with and without conjunctivitis. Low HC, Powell CC, Veir JK, Hawley JR, Lappin MR. https://doi.org/10.2460/ajvr.68.6.643
Identification of ocular matrix metalloproteinases present within the aqueous humor and iridocorneal drainage angle tissue of normal and glaucomatous canine eyes. Weinstein WL, Dietrich UM, Sapienza JS, Carmichael KP, Moore PA, Krunkosky ™. https://doi.org/10.1111/j.1463-5224.2007.00586.x
2006
In vitro fungistatic and fungicidal activities of silver sulfadiazine and natamycin on pathogenic fungi isolated from horses with keratomycosis. Betbeze CM, Wu CC, Krohne SG, Stiles J. https://doi.org/10.2460/ajvr.67.10.1788
Evaluation of concentration of voriconazole in aqueous humor after topical and oral administration in horses. Clode AB, Davis JL, Salmon J, Michau TM, Gilger BC. https://doi.org/10.2460/ajvr.67.2.296
